Biodegradable calcium phosphate nanoparticles for cancer therapy

Suicide gene delivery by calcium phosphate nanoparticles: a novel method of targeted therapy for gastric cancer.

Plant-Based Calcium Fructoborate as Boron-Carrying Nanoparticles for Neutron Cancer Therapy

Boron neutron capture therapy (BNCT) is an effective clinical method in cancer treatment based on fission reactions and nuclear capturing. In this method, use of the best boron-containing agents for boron therapy and boron delivery agent for transfer to the infectious site are the key points for  efficienct treatment. Our research indicated that calcium fructoborate(CF) was the best compound as...

Biodegradable Nanoparticles for Intra-articular Therapy

Osteoarthritis (OA) is a chronic degenerative joint disease characterized by progressive loss of articular cartilage which leads to severe pain and restricted mobility in the patients. Age, excessive joint loading, or sports injury are the factors known to increase the risk of joint degeneration thus leading to OA. Many techniques have been employed in OA therapy but none of them has given sati...

Nanoparticles of biodegradable polymers for cancer treatment.

Chemotherapy drug delivery from calcium phosphate nanoparticles

Calcium phosphate nanoparticles (nanoCaP) conjugated with cis-diamminedichloroplatinum (CDDP, cisplatin) were prepared through the electrostatic binding of an aquated species of cisplatin to the nanoCaP in a chloride-free solution. The agglomeration of the nanoCaP that typically occurs during synthesis of CaP was controlled through the addition of DARVAN 811 immediately after precipitation and ...